Tobacco has been used and cultivated in America for a very long time, 10,000 years by some accounts. High nicotine content varieties of Nicotiana tabacum and Nicotiana rustica were prized by many tribes.
The flowers of the original flowering tobacco (Nicotiana alata) are very fragrant and open at night. During the day, the night flowering varieties might look weedy. Some more recent varieties open all day, but are not always so fragrant. If the fragrance is your main attraction, your better bet is with the white, night-flowering varieties. The colored versions come in pink, purple or red.
Regular water, well drained soil, with good organic matter content.