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Chromolaena odorata grows in many soil types but prefers well-drained soils, (PIER, 2003). It does not tolerate shade and thrives well in open areas (FAO). Requires disturbance to become established. It will not grow in waterlogged or saline soils. It can occur in most tropical and sub-tropical terrestrial habitats below 1000 m altitude, except for undisturbed rainforest. It requires at least 1200 mm annual rainfall, but tolerates severe dry seasons

Chromolaena odorata is used as a traditional medicine in Vietnam, the aqueous extract and the decoction from the leaves of this plant have been used throughout Vietnam for the treatment of soft tissue wounds, burn wounds, and skin infections.